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  • Hepcinat (Sofosbuvir) is a breakthrough treatment for Hepatitis C infections
11:30, 12 червня 2015 р.

Hepcinat (Sofosbuvir) is a breakthrough treatment for Hepatitis C infections

Its strategy of action is to kill the "silent" virus when not letting it to multiply. Hepcinat (or better known as sofosbuvir) is a progress in treatment for hepatitis C infections. Its clever mechanism involves inhibiting the enzyme which is necessary for the virus if it is to multiply. A complete cure may even be expected. Chronic hepatitis C is a serious infection of the liver which occurs following an infection with the hepatitis C virus. When reaching the cells of the liver, the virus begins to reproduce, which it achieves with the help of copying its DNA and RNA. This medicine is also known as a nucleotide polymerase inhibitor, and it affects directly the virus itself.

After oral administration, it undergoes a process of intracellular metabolism in which it is turned into its active form. It starts to work afterwards, whereupon it actively targets the enzyme that is used by the virus to produce RNA chains (HCV NS5B RNA-dependent RNA polymerase). This can help to kill viral reproduction. Treatment of genotypes 1, 2, 3 and 4 is possible with this medicine; nevertheless it is always used together with other medications and never alone in order to get unwanted results.

Dosage and prescription Hepcinat (Sofosbuvir) film coated tablets each contain 400mg of the main component. The dosage scheme must be administered basing on individual needs of the patient. The physician in charge of treatment will decide what dose to take, and will vary according to the viral genotype that is being treated. Adult patients will usually be recommended by their physician to take 1 tablet a day, and it can be administered during a meal or else without food. Those suffering from GT1 or GT4 (genotype 1 or 4) may be ordered by the physician to take it alongside ribavirin and peginterferon alfa, with treatment lasting for a period of 12 weeks. In contrast to this, GT2 (genotype 2) is usually treated for 12 weeks, and it is taken together with ribavirin. GT3 (genotype 3) requires 24 weeks of treatment in combination with ribavirin. Patients must only take it according to the instructions provided to them by the physician in charge of treatment.

Special precautions Patients who are undergoing treatment for Hepatitis C with Hepcinat (Sofosbuvir) will require frequent visits to their physician or the hospital so that routine blood tests can be done to check the condition. The frequency at which these tests are required will be determined by your physician. Your health condition will decide how long you should do.

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